Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons

This review provides insight into the role of engineered T-cell receptors (TCRs) in immunotherapy. Novel approaches have been developed to boost anticancer immune system, including targeting new antigens, manufacturing new engineered or modified TCRs, and creating a safety switch for endo-suicide ge...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Zhao, Qijie, Jiang, Yu, Xiang, Shixin, Kaboli, Parham Jabbarzadeh, Shen, Jing, Zhao, Yueshui, Wu, Xu, Du, Fukuan, Li, Mingxing, Cho, Chi Hin, Li, Jing, Wen, Qinglian, Liu, Tao, Yi, Tao, Xiao, Zhangang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042275/
https://ncbi.nlm.nih.gov/pubmed/33859650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.658753
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