Whole genome deep sequencing analysis of viral quasispecies diversity and evolution in HBeAg seroconverters

BACKGROUND & AIMS: We aimed to investigate how viral quasispecies of the HBV whole genome evolves and diversifies in response to HBeAg seroconversion and viral control utilising next-generation sequencing (NGS). METHODS: Fifty HBeAg-positive chronic hepatitis B patients, including 18 treatment-n...

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Podrobná bibliografie
Vydáno v:JHEP Rep
Hlavní autoři: Lin, Su-Ru, Yang, Ta-Yu, Peng, Cheng-Yuan, Lin, You-Yu, Dai, Chia-Yen, Wang, Hurng-Yi, Su, Tung-Hung, Tseng, Tai-Chung, Liu, I-Jung, Cheng, Huei-Ru, Shen, Yueh-Chi, Wu, Fang-Yi, Liu, Chun-Jen, Chen, Ding-Shinn, Chen, Pei-Jer, Yang, Hung-Chih, Kao, Jia-Horng
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042178/
https://ncbi.nlm.nih.gov/pubmed/33870157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100254
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