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Transcriptomic analysis of human brain microvascular endothelial cells exposed to laminin binding protein (adhesion lipoprotein) and Streptococcus pneumoniae

Streptococcus pneumoniae invades the CNS and triggers a strong cellular response. To date, signaling events that occur in the human brain microvascular endothelial cells (hBMECs), in response to pneumococci or its surface adhesins are not mapped comprehensively. We evaluated the response of hBMECs t...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jiménez-Munguía, Irene, Tomečková, Zuzana, Mochnáčová, Evelína, Bhide, Katarína, Majerová, Petra, Bhide, Mangesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041795/
https://ncbi.nlm.nih.gov/pubmed/33846455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87021-4
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