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Promising potential of [(177)Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy—a preclinical study using a syngeneic breast cancer model

PURPOSE: It was previously demonstrated that radiation effects can enhance the therapy outcome of immune checkpoint inhibitors. In this study, a syngeneic breast tumor mouse model was used to investigate the effect of [(177)Lu]Lu-DOTA-folate as an immune stimulus to enhance anti-CTLA-4 immunotherapy...

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Bibliografske podrobnosti
izdano v:Eur J Nucl Med Mol Imaging
Main Authors: Guzik, Patrycja, Siwowska, Klaudia, Fang, Hsin-Yu, Cohrs, Susan, Bernhardt, Peter, Schibli, Roger, Müller, Cristina
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041666/
https://ncbi.nlm.nih.gov/pubmed/33078260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05054-9
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