An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence

A high-throughput systematic evolution of ligands by exponential enrichment assay was applied to 371 putative TFs in Pseudomonas aeruginosa, which resulted in the robust enrichment of 199 unique sequence motifs describing the binding specificities of 182 TFs. By scanning the genome, we predicted in...

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Bibliographic Details
Published in:eLife
Main Authors: Wang, Tingting, Sun, Wenju, Fan, Ligang, Hua, Canfeng, Wu, Nan, Fan, Shaorong, Zhang, Jilin, Deng, Xin, Yan, Jian
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2021
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041468/
https://ncbi.nlm.nih.gov/pubmed/33779544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61885
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