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Meta-Analysis of Rare Adverse Events in Randomized Clinical Trials: Bayesian and Frequentist Methods

BACKGROUND/AIMS: Regulatory approval of a drug or device involves an assessment of not only the benefits but also the risks of adverse events associated with the therapeutic agent. Although randomized controlled trials (RCTs) are the gold standard for evaluating effectiveness, the number of treated...

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Vydáno v:Clin Trials
Hlavní autoři: Hong, Hwanhee, Wang, Chenguang, Rosner, Gary L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041270/
https://ncbi.nlm.nih.gov/pubmed/33258698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774520969136
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