Extracellular vesicles derived from umbilical cord mesenchymal stromal cells alleviate pulmonary fibrosis by means of transforming growth factor-β signaling inhibition

BACKGROUND: Pulmonary fibrosis (PF), the end point of interstitial lung diseases, is characterized by myofibroblast over differentiation and excessive extracellular matrix accumulation, leading to progressive organ dysfunction and usually a terminal outcome. Studies have shown that umbilical cord-de...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Shi, Liyan, Ren, Jing, Li, Jiping, Wang, Dongxu, Wang, Yusu, Qin, Tao, Li, Xiuying, Zhang, Guokun, Li, Chunyi, Wang, Yimin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041243/
https://ncbi.nlm.nih.gov/pubmed/33845892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02296-8
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