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Salting the soil: Targeting the microenvironment of brain metastases

Paget’s ‘seed and soil’ hypothesis of metastatic spread has acted as a foundation of the field for over a century, with continued evolution as mechanisms of the process have been elucidated. The CNS presents a unique soil through this lens, relatively isolated from peripheral circulation and immune...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Srinivasan, Ethan S., Tan, Aaron C., Anders, Carey K., Pendergast, Ann Marie, Sipkins, Dorothy A., Ashley, David M., Fecci, Peter E., Khasraw, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041238/
https://ncbi.nlm.nih.gov/pubmed/33402399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0579
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