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Bacteria primed by antimicrobial peptides develop tolerance and persist

Antimicrobial peptides (AMPs) are key components of innate immune defenses. Because of the antibiotic crisis, AMPs have also come into focus as new drugs. Here, we explore whether prior exposure to sub-lethal doses of AMPs increases bacterial survival and abets the evolution of resistance. We show t...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Rodríguez-Rojas, Alexandro, Baeder, Desiree Y., Johnston, Paul, Regoes, Roland R., Rolff, Jens
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041211/
https://ncbi.nlm.nih.gov/pubmed/33788905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009443
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