Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition

Rift Valley fever virus (RVFV), an emerging arboviral and zoonotic bunyavirus, causes severe disease in livestock and humans. Here, we report the isolation of a panel of monoclonal antibodies (mAbs) from the B cells of immune individuals following natural infection in Kenya or immunization with MP-1...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chapman, Nathaniel S., Zhao, Haiyan, Kose, Nurgun, Westover, Jonna B., Kalveram, Birte, Bombardi, Robin, Rodriguez, Jessica, Sutton, Rachel, Genualdi, Joseph, LaBeaud, A. Desiree, Mutuku, Francis M., Pittman, Phillip R., Freiberg, Alexander N., Gowen, Brian B., Fremont, Daved H., Crowe, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040655/
https://ncbi.nlm.nih.gov/pubmed/33782133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025642118
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