MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types

Background & Aims: Liver fibrosis is a common consequence of chronic liver injury and is characterized by the accumulation of extracellular matrix mainly generated from activated hepatic stellate cells (HSCs). At present, the mechanisms underlying liver fibrogenesis remain obscure and effective...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Biol Sci
Main Authors: Wang, Xiaolin, Seo, Wonhyo, Park, Seol Hee, Fu, Yaojie, Hwang, Seonghwan, Rodrigues, Robim M., Feng, Dechun, Gao, Bin, He, Yong
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2021
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040312/
https://ncbi.nlm.nih.gov/pubmed/33867837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.58365
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