Isochromanoindolenines suppress triple-negative breast cancer cell proliferation partially via inhibiting Akt activation

As the most malignant subtype of breast cancers, triple-negative breast cancer (TNBC) lacks effective targeted therapeutics clinically to date. In this study, one lead compound FZU-0025-065 with isochromanoindolenine scaffold was identified by a cell-based screening. Among nine breast cancer cell li...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Jiang, Xiaoyan, Zhi, Xu, Zhang, Peixia, Zhou, Zhongmei, Ye, Jinxiang, Gao, Yu, Wang, Xinye, Yang, Chuanyu, Chen, Haijun, Liu, Rong, Chen, Ceshi
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040301/
https://ncbi.nlm.nih.gov/pubmed/33867823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.48170
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