High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke

BACKGROUND: A high-salt diet (HSD) is one of the major risk factors for acute ischemic stroke (AIS). As a potential mechanism, surplus salt intake primes macrophages towards a proinflammatory phenotype. In this study, whether HSD could blunt the efferocytic capability of macrophages after ischemic s...

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Publicado en:J Neuroinflammation
Main Authors: Hu, Mengyan, Lin, Yinyao, Men, Xuejiao, Wang, Shisi, Sun, Xiaobo, Zhu, Qiang, Lu, Danli, Liu, Sanxin, Zhang, Bingjun, Cai, Wei, Lu, Zhengqi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040220/
https://ncbi.nlm.nih.gov/pubmed/33845849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02144-9
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