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The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1(+) hematoendothelial progenitors

Little is known about extracellular matrix (ECM) contributions to formation of the earliest cell lineages in the embryo. Here, we show that the proteoglycan versican and glycosaminoglycan hyaluronan are associated with emerging Flk1(+) hematoendothelial progenitors at gastrulation. The mouse versica...

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Bibliografiske detaljer
Udgivet i:Matrix Biol
Main Authors: Nandadasa, Sumeda, O’Donnell, Anna, Murao, Ayako, Yamaguchi, Yu, Midura, Ronald J., Olson, Lorin, Apte, Suneel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039968/
https://ncbi.nlm.nih.gov/pubmed/33454424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2021.01.002
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