Yüklüyor......

Homogeneous tumor targeting with a single dose of HER2-targeted albumin-binding domain-fused nanobody-drug conjugates results in long-lasting tumor remission in mice

Background: The non-homogenous distribution of antibody-drug conjugates (ADCs) within solid tumors is a major limiting factor for their wide clinical application. Nanobodies have been shown to rapidly penetrate into xenografts, achieving more homogeneous tumor targeting. However, their rapid renal c...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Theranostics
Asıl Yazarlar: Xenaki, Katerina T, Dorresteijn, Bram, Muns, Joey A, Adamzek, Kevin, Doulkeridou, Sofia, Houthoff, HendrikJan, Oliveira, Sabrina, van Bergen en Henegouwen, Paul MP
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039960/
https://ncbi.nlm.nih.gov/pubmed/33859761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.57510
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!