Traditional Chinese Formula Xiaoyaosan Alleviates Depressive-Like Behavior in CUMS Mice by Regulating PEBP1-GPX4-Mediated Ferroptosis in the Hippocampus

BACKGROUND: At present, the pathogenesis of depression is not fully understood, and nearly half of depression patients experience no obvious effects during treatment. This study aimed to establish a depression mouse model to explore the possible role of ferroptosis in the pathogenesis of depression,...

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Bibliografiske detaljer
Udgivet i:Neuropsychiatr Dis Treat
Main Authors: Jiao, Haiyan, Yang, Hongjun, Yan, Zhiyi, Chen, Jianbei, Xu, Mengbai, Jiang, Youming, Liu, Yueyun, Xue, Zhe, Ma, Qingyu, Li, Xiaojuan, Chen, Jiaxu
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039849/
https://ncbi.nlm.nih.gov/pubmed/33854318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S302443
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