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The mitochondrial-targeted reactive species scavenger JP4-039 prevents sulfite-induced alterations in antioxidant defenses, energy transfer, and cell death signaling in striatum of rats

Sulfite oxidase (SO) deficiency is a disorder caused either by isolated deficiency of SO or by defects in the synthesis of its molybdenum cofactor. It is characterized biochemically by tissue sulfite accumulation. Patients present with seizures, progressive neurological damage, and basal ganglia abn...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Inherit Metab Dis
Prif Awduron: Glänzel, Nícolas Manzke, Grings, Mateus, da Rosa-Junior, Nevton Teixeira, Cereta de Carvalho, Leila Maria, Mohsen, Al-Walid, Wipf, Peter, Wajner, Moacir, Vockley, Jerry, Leipnitz, Guilhian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039837/
https://ncbi.nlm.nih.gov/pubmed/32882059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12310
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