Loss of bound zinc facilitates amyloid fibril formation of leukocyte-cell-derived chemotaxin 2 (LECT2)

Aggregation of the circulating protein leukocyte-cell-derived chemotaxin 2 (LECT2) causes amyloidosis of LECT2 (ALECT2), one of the most prevalent forms of systemic amyloidosis affecting the kidney and liver. The I40V mutation is thought to be necessary but not sufficient for ALECT2, with a second,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ha, Jeung-Hoi, Tu, Ho-Chou, Wilkens, Stephan, Loh, Stewart N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Accelerated Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039541/
https://ncbi.nlm.nih.gov/pubmed/33617884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100446
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker