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Weighted Gene Co-expression Network Analysis Reveals Different Immunity but Shared Renal Pathology Between IgA Nephropathy and Lupus Nephritis

Both IgA nephropathy (IgAN) and lupus nephritis (LN) are immunity-related diseases with a complex, polygenic, and pleiotropic genetic architecture. However, the mechanism by which the genetic variants impart immunity or renal dysfunction remains to be clarified. In this study, using gene expression...

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Publicado en:Front Genet
Main Authors: Jia, Ni-Ya, Liu, Xing-Zi, Zhang, Zhao, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039522/
https://ncbi.nlm.nih.gov/pubmed/33854525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.634171
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