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Dissecting the role of glutamine in seeding peptide aggregation

Poly glutamine and glutamine-rich peptides play a central role in a plethora of pathological aggregation events. However, biophysical characterization of soluble oligomers -the most toxic species involved in these processes- remains elusive due to their structural heterogeneity and dynamical nature....

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Barrera, Exequiel E., Zonta, Francesco, Pantano, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039506/
https://ncbi.nlm.nih.gov/pubmed/33868596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.02.014
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