Pilot Study on Quantitative Cervical Cord and Muscular MRI in Spinal Muscular Atrophy: Promising Biomarkers of Disease Evolution and Treatment?

Introduction: Nusinersen is a recent promising therapy approved for the treatment of spinal muscular atrophy (SMA), a rare disease characterized by the degeneration of alpha motor neurons (αMN) in the spinal cord (SC) leading to progressive muscle atrophy and dysfunction. Muscle and cervical SC quan...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Savini, Giovanni, Asteggiano, Carlo, Paoletti, Matteo, Parravicini, Stefano, Pezzotti, Elena, Solazzo, Francesca, Muzic, Shaun I., Santini, Francesco, Deligianni, Xeni, Gardani, Alice, Germani, Giancarlo, Farina, Lisa M., Bergsland, Niels, Gandini Wheeler-Kingshott, Claudia A. M., Berardinelli, Angela, Bastianello, Stefano, Pichiecchio, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039452/
https://ncbi.nlm.nih.gov/pubmed/33854470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.613834
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