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Transcription Factor Reprogramming in the Inner Ear: Turning on Cell Fate Switches to Regenerate Sensory Hair Cells

Non-mammalian vertebrates can restore their auditory and vestibular hair cells naturally by triggering the regeneration of adjacent supporting cells. The transcription factor ATOH1 is a key regulator of hair cell development and regeneration in the inner ear. Following the death of hair cells, suppo...

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Pubblicato in:Front Cell Neurosci
Autori principali: Iyer, Amrita A., Groves, Andrew K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039129/
https://ncbi.nlm.nih.gov/pubmed/33854418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.660748
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