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Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway

Microglia are the resident immune effector cells of the central nervous system (CNS) rapidly reacting to various pathological stimuli to maintain CNS homeostasis. However, microglial reactions in the CNS may also worsen neurological disorders. Hence, the phenotypic analysis of microglia in healthy t...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Uriarte Huarte, Oihane, Kyriakis, Dimitrios, Heurtaux, Tony, Pires-Afonso, Yolanda, Grzyb, Kamil, Halder, Rashi, Buttini, Manuel, Skupin, Alexander, Mittelbronn, Michel, Michelucci, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039119/
https://ncbi.nlm.nih.gov/pubmed/33854507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.639613
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