Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53–Bcl-2 intrinsic apoptosis pathway

BACKGROUND: Gastric cancer (GC) with hepatic metastasis has a poor prognosis. Understanding the molecular mechanisms involved in hepatic metastasis may contribute to the development of sensitive diagnostic biomarkers and novel therapeutic strategies. METHODS: We performed transcriptome analysis of s...

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Pubblicato in:Br J Cancer
Autori principali: Miwa, Takashi, Kanda, Mitsuro, Shimizu, Dai, Umeda, Shinichi, Sawaki, Koichi, Tanaka, Haruyoshi, Tanaka, Chie, Hattori, Norifumi, Hayashi, Masamichi, Yamada, Suguru, Nakayama, Goro, Koike, Masahiko, Kodera, Yasuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039033/
https://ncbi.nlm.nih.gov/pubmed/33531692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01271-7
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