RNA and DNA G-quadruplexes bind to human dicer and inhibit its activity

Guanine (G)-rich single-stranded nucleic acids can adopt G-quadruplex structures. Accumulating evidence indicates that G-quadruplexes serve important regulatory roles in fundamental biological processes such as DNA replication, transcription, and translation, while aberrant G-quadruplex formation is...

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Pubblicato in:Cell Mol Life Sci
Autori principali: Koralewska, Natalia, Szczepanska, Agnieszka, Ciechanowska, Kinga, Wojnicka, Marta, Pokornowska, Maria, Milewski, Marek C., Gudanis, Dorota, Baranowski, Daniel, Nithin, Chandran, Bujnicki, Janusz M., Gdaniec, Zofia, Figlerowicz, Marek, Kurzynska-Kokorniak, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038994/
https://ncbi.nlm.nih.gov/pubmed/33733306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03795-w
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