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Structural basis of the human Scribble–Vangl2 association in health and disease

Scribble is a critical cell polarity regulator that has been shown to work as either an oncogene or tumor suppressor in a context dependent manner, and also impacts cell migration, tissue architecture and immunity. Mutations in Scribble lead to neural tube defects in mice and humans, which has been...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: How, Jing Yuan, Stephens, Rebecca K., Lim, Krystle Y.B., Humbert, Patrick O., Kvansakul, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038854/
https://ncbi.nlm.nih.gov/pubmed/33684218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200816
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