β-Sitosterol Circumvents Obesity Induced Inflammation and Insulin Resistance by down-Regulating IKKβ/NF-κB and JNK Signaling Pathway in Adipocytes of Type 2 Diabetic Rats

β-sitosterol (SIT), the most abundant bioactive component of vegetable oil and other plants, is a highly potent antidiabetic drug. Our previous studies show that SIT controls hyperglycemia and insulin resistance by activating insulin receptor and glucose transporter 4 (GLUT-4) in the adipocytes of o...

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Publicat a:Molecules
Autors principals: Jayaraman, Selvaraj, Devarajan, Nalini, Rajagopal, Ponnulakshmi, Babu, Shyamaladevi, Ganesan, Senthil Kumar, Veeraraghavan, Vishnu Priya, Palanisamy, Chella Perumal, Cui, Bo, Periyasamy, Vijayalakshmi, Chandrasekar, Kirubhanand
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038823/
https://ncbi.nlm.nih.gov/pubmed/33917607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072101
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