Circulating Tumor DNA Reflects Uveal Melanoma Responses to Protein Kinase C Inhibition

SIMPLE SUMMARY: Uveal melanoma (UM) is a rare cancer, with no effective standard systemic therapy in the metastatic setting. Over 95% of UM harbor activating driver mutations that can be detected in the circulation. In this study, circulating tumor DNA (ctDNA) was measured in 17 metastatic UM patien...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Park, John J., Diefenbach, Russell J., Byrne, Natalie, Long, Georgina V., Scolyer, Richard A., Gray, Elin S., Carlino, Matteo S., Rizos, Helen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038771/
https://ncbi.nlm.nih.gov/pubmed/33917514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071740
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