Uptake and use of a vaginal ring containing dapivirine for HIV-1 prevention in African women: an open-label extension study

BACKGROUND: Two Phase III clinical trials showed that use of a monthly vaginal ring containing 25 mg dapivirine was well-tolerated and reduced HIV-1 incidence in women by approximately 30% compared to placebo (3.3 and 4.1 versus 4.5 and 6.1 per 100 person-years). Understanding use of the dapivirine...

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Publicado no:Lancet HIV
Main Authors: Baeten, Jared M., Palanee-Phillips, Thesla, Mgodi, Nyaradzo M., Mayo, Ashley J., Szydlo, Daniel W., Ramjee, Gita, Mirembe, Brenda Gati, Mhlanga, Felix, Hunidzarira, Portia, Mansoor, Leila E., Siva, Samantha, Govender, Vaneshree, Makanani, Bonus, Naidoo, Logashvari, Singh, Nishanta, Nair, Gonasagrie, Chinula, Lameck, Parikh, Urvi M., Mellors, John W., Balán, Iván C., Ngure, Kenneth, van der Straten, Ariane, Scheckter, Rachel, Garcia, Morgan, Peda, Melissa, Patterson, Karen, Livant, Edward, Bunge, Katherine, Singh, Devika, Jacobson, Cindy, Jiao, Yuqing, Hendrix, Craig W., Chirenje, Zvavahera M., Nakabiito, Clemensia, Taha, Taha E., Jones, Judith, Torjesen, Kristine, Nel, Annalene, Rosenberg, Zeda, Soto-Torres, Lydia E., Hillier, Sharon L., Brown, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038210/
https://ncbi.nlm.nih.gov/pubmed/33539762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3018(20)30304-0
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