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Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial–Mesenchymal State in Cancer Cells

Epithelial–mesenchymal transition (EMT) is important for the initial steps of metastasis. Although it is well accepted that the nucleoside diphosphate kinase NME1 is a metastasis suppressor, its effect on EMT remains poorly documented, as does that of its closely related isoform, NME2. Here, by usin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Huna, Anda, Nawrocki-Raby, Béatrice, Padilla-Benavides, Teresita, Gavard, Julie, Coscoy, Sylvie, Bernard, David, Boissan, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038181/
https://ncbi.nlm.nih.gov/pubmed/33918324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073718
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