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Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning

SIMPLE SUMMARY: Breast cancer (BrCa) is characterized by aberrant DNA methylation. We leveraged high-throughput methylation data from BrCa and normal breast tissues and identified 11,176 to 27,786 differentially methylated genes (DMGs) against clinically relevant end-points. Innovative automated mac...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Panagopoulou, Maria, Karaglani, Makrina, Manolopoulos, Vangelis G., Iliopoulos, Ioannis, Tsamardinos, Ioannis, Chatzaki, Ekaterini
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037759/
https://ncbi.nlm.nih.gov/pubmed/33918195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071677
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