Foxp3 Silencing with Antisense Oligonucleotide Improves Immunogenicity of an Adjuvanted Recombinant Vaccine against Sporothrix schenckii

Background: In recent years, there has been great interest in developing molecular adjuvants based on antisense oligonucleotides (ASOs) targeting immunosuppressor pathways with inhibitory effects on regulatory T cells (Tregs) to improve immunogenicity and vaccine efficacy. We aim to evaluate the imm...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Batista-Duharte, Alexander, Sendra, Luis, Herrero, Maria José, Portuondo, Deivys Leandro, Téllez-Martínez, Damiana, Olivera, Gladys, Fernández-Delgado, Manuel, Javega, Beatriz, Herrera, Guadalupe, Martínez, Alicia, Costa, Paulo Inacio, Zeppone Carlos, Iracilda, Aliño, Salvador Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037512/
https://ncbi.nlm.nih.gov/pubmed/33801683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073470
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