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Silencing of Sphingosine kinase 1 Affects Maturation Pathways in Mouse Neonatal Cardiomyocytes

Sphingosine kinase-1 (Sphk1) and its product, sphingosine-1-phosphate (S1P) are important regulators of cardiac growth and function. Numerous studies have reported that Sphk1/S1P signaling is essential for embryonic cardiac development and promotes pathological cardiac hypertrophy in adulthood. Howe...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Jozefczuk, Ewelina, Szczepaniak, Piotr, Guzik, Tomasz Jan, Siedlinski, Mateusz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037404/
https://ncbi.nlm.nih.gov/pubmed/33807180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073616
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