Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains

Alzheimer’s disease (AD) is a neurodegenerative disease, characterized histopathologically by intra-neuronal tau-related lesions and by the accumulation of amyloid β-peptide (Aβ) in the brain parenchyma and around cerebral blood vessels. According to the vascular hypothesis of AD, an alteration in t...

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Pubblicato in:Int J Mol Sci
Autori principali: Soto-Rojas, Luis O., Campa-Córdoba, B. Berenice, Harrington, Charles R., Salas-Casas, Andrés, Hernandes-Alejandro, Mario, Villanueva-Fierro, Ignacio, Bravo-Muñoz, Marely, Garcés-Ramírez, Linda, De La Cruz-López, Fidel, Ontiveros-Torres, Miguel Ángel, Gevorkian, Goar, Pacheco-Herrero, Mar, Luna-Muñoz, José
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036769/
https://ncbi.nlm.nih.gov/pubmed/33915754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073654
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