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HDAC6 Signaling at Primary Cilia Promotes Proliferation and Restricts Differentiation of Glioma Cells

SIMPLE SUMMARY: Glioblastoma is the most common and lethal brain tumor in adults because it becomes resistant to virtually every treatment. Histone deacetylase 6 (HDAC6), which is located primarily in the cytoplasm, has a unique role in promoting the disassembly of cells’ primary cilium, a non-motil...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Shi, Ping, Hoang-Minh, Lan B., Tian, Jia, Cheng, Alice, Basrai, Reemsha, Kalaria, Neil, Lebowitz, Joseph J., Khoshbouei, Habibeh, Deleyrolle, Loic P., Sarkisian, Matthew R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036575/
https://ncbi.nlm.nih.gov/pubmed/33915983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071644
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