Granulibacter bethesdensis, a Pathogen from Patients with Chronic Granulomatous Disease, Produces a Penta-Acylated Hypostimulatory Glycero-D-talo-oct-2-ulosonic Acid–Lipid A Glycolipid (Ko-Lipid A)

Granulibacter bethesdensis can infect patients with chronic granulomatous disease, an immunodeficiency caused by reduced phagocyte NADPH oxidase function. Intact G. bethesdensis (Gb) is hypostimulatory compared to Escherichia coli, i.e., cytokine production in human blood requires 10–100 times more...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Muszyński, Artur, Zarember, Kol A., Heiss, Christian, Shiloach, Joseph, Berg, Lars J., Audley, John, Kozyr, Arina, Greenberg, David E., Holland, Steven M., Malech, Harry L., Azadi, Parastoo, Carlson, Russell W., Gallin, John I.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036547/
https://ncbi.nlm.nih.gov/pubmed/33804872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073303
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