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Nickel-Catalyzed Kumada Cross-Coupling Reactions of Tertiary Alkylmagnesium Halides and Aryl Bromides/Triflates

We report a Ni-catalyzed process for the cross-coupling of tertiary alkyl nucleophiles and aryl bromides. This process is extremely general for a wide range of electrophiles and generally occurs with a ratio of retention to isomerization >30:1. The same procedure also accommodates the use of aryl...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Joshi-Pangu, Amruta, Wang, Chao-Yuan, Biscoe, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036247/
https://ncbi.nlm.nih.gov/pubmed/21553878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202769t
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