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Evaluating the surrogacy of multiple vaccine-induced immune response biomarkers in HIV vaccine trials
Identifying biomarkers as surrogates for clinical endpoints in randomized vaccine trials is useful for reducing study duration and costs, relieving participants of unnecessary discomfort, and understanding vaccine-effect mechanism. In this article, we use risk models with multiple vaccine-induced im...
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| Publié dans: | Biostatistics |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8035998/ https://ncbi.nlm.nih.gov/pubmed/31631216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxz039 |
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