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A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease

BACKGROUND: Aducanumab is an anti-amyloid-β (Aβ) antibody that achieved reduced amyloid pathology in Alzheimer’s disease (AD) trials; however, it is controversial whether it also improved cognition, which has been suggested would require a sufficiently high cumulative dose of the antibody in the bra...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Alzheimers Res Ther
Main Authors: Leinenga, Gerhard, Koh, Wee Kiat, Götz, Jürgen
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035770/
https://ncbi.nlm.nih.gov/pubmed/33836798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00809-4
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