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Type I interferon signaling limits viral vector priming of CD8(+) T cells during initiation of vitiligo and melanoma immunotherapy

Vitiligo is an autoimmune skin disease in which epidermal melanocytes are targeted for destruction by CD8(+) T cells specific for melanocyte/melanoma-shared antigens. IFNγ is the central cytokine driving disease but the role of type I IFN in vitiligo remains unclear. We investigated the functional r...

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Bibliografische gegevens
Gepubliceerd in:Pigment Cell Melanoma Res
Hoofdauteurs: Riding, Rebecca L., Richmond, Jillian M., Fukuda, Keitaro, Harris, John E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035367/
https://ncbi.nlm.nih.gov/pubmed/33040466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12935
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