Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice

The accumulation of adenosine is strongly correlated with the need for sleep and the detection of sleep pressure is antagonised by caffeine. Caffeine also affects the circadian timing system directly and independently of sleep physiology, but how caffeine mediates these effects upon the circadian cl...

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Pubblicato in:Nat Commun
Autori principali: Jagannath, Aarti, Varga, Norbert, Dallmann, Robert, Rando, Gianpaolo, Gosselin, Pauline, Ebrahimjee, Farid, Taylor, Lewis, Mosneagu, Dragos, Stefaniak, Jakub, Walsh, Steven, Palumaa, Teele, Di Pretoro, Simona, Sanghani, Harshmeena, Wakaf, Zeinab, Churchill, Grant C., Galione, Antony, Peirson, Stuart N., Boison, Detlev, Brown, Steven A., Foster, Russell G., Vasudevan, Sridhar R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035342/
https://ncbi.nlm.nih.gov/pubmed/33837202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22179-z
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