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Discrete binding patterns of two heparin-reactive proteins, basic fibroblast growth factor and peptide p5R, in amyloid-laden and healthy mice

Peptide p5R is a synthetic, polybasic, heparin-binding peptide that preferentially reacts with amyloid deposits in vivo and in tissue sections. Basic fibroblast growth factor (bFGF()) similarly interacts with heparin-like molecules, notably heparan sulfate proteoglycans (HSPG), in the extracellular...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Martin, Emily B., Donnell, Robert, Richey, Tina, Stuckey, Alan, Kennel, Stephen J., Wall, Jonathan S.
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035312/
https://ncbi.nlm.nih.gov/pubmed/33744761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.03.054
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