Serum-derived exosomal PD-L1 expression to predict anti-PD-1 response and in patients with non-small cell lung cancer

PD-L1 expression is the most useful predictive biomarker for immunotherapy efficacy on non-small cell lung cancer (NSCLC), and CD8+ tumor-infiltrating lymphocytes (CD8+ TILs) play an essential role in the clinical activity of immunotherapy. PD-L1 is found on the exosome’s surface, and PD-L1 expressi...

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Опубликовано в: :Sci Rep
Главные авторы: Shimada, Yoshihisa, Matsubayashi, Jun, Kudo, Yujin, Maehara, Sachio, Takeuchi, Susumu, Hagiwara, Masaru, Kakihana, Masatoshi, Ohira, Tatsuo, Nagao, Toshitaka, Ikeda, Norihiko
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035184/
https://ncbi.nlm.nih.gov/pubmed/33837261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87575-3
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