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Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease

Protein lysine methylation is a crucial post-translational modification that regulates the functions of both histone and non-histone proteins. Deregulation of the enzymes or’writers’ of protein lysine methylation, lysine methyltransferases (KMTs), is implicated in the cause of many diseases, includi...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Bhat, Kamakoti P., Kaniskan, H. Ümit, Jin, Jian, Gozani, Or
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035164/
https://ncbi.nlm.nih.gov/pubmed/33469207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-00108-x
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