Evolution of mammalian longevity: age-related increase in autophagy in bats compared to other mammals

Autophagy maintains cellular homeostasis and its dysfunction has been implicated in aging. Bats are the longest-lived mammals for their size, but the molecular mechanisms underlying their extended healthspan are not well understood. Here, drawing on >8 years of mark-recapture field studies, we re...

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Foilsithe in:Aging (Albany NY)
Main Authors: Kacprzyk, Joanna, Locatelli, Andrea G., Hughes, Graham M., Huang, Zixia, Clarke, Michael, Gorbunova, Vera, Sacchi, Carlotta, Stewart, Gavin S., Teeling, Emma C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals 2021
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034928/
https://ncbi.nlm.nih.gov/pubmed/33744862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202852
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