Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

Doxorubicin (DOX) is a common drug in cancer chemotherapy, and its high DNA-binding affinity can be harnessed in preparing DOX-loaded DNA nanostructures for targeted delivery and therapeutics. Although DOX has been widely studied, the existing literature of DOX-loaded DNA-carriers remains limited an...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Ijäs, Heini, Shen, Boxuan, Heuer-Jungemann, Amelie, Keller, Adrian, Kostiainen, Mauri A, Liedl, Tim, Ihalainen, Janne A, Linko, Veikko
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Chemical Biology and Nucleic Acid Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034656/
https://ncbi.nlm.nih.gov/pubmed/33660776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab097
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