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Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

Epstein-Barr virus (EBV), a herpes virus also termed HHV 4 and the first identified human tumor virus, establishes a stable, long-term latent infection in human B cells, its preferred host. Upon induction of EBV’s lytic phase, the latently infected cells turn into a virus factory, a process that is...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Buschle, Alexander, Mrozek-Gorska, Paulina, Cernilogar, Filippo M, Ettinger, Andreas, Pich, Dagmar, Krebs, Stefan, Mocanu, Bianca, Blum, Helmut, Schotta, Gunnar, Straub, Tobias, Hammerschmidt, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034645/
https://ncbi.nlm.nih.gov/pubmed/33675667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab099
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