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Hydrogen sulphide reduces hyperhomocysteinaemia‐induced endothelial ER stress by sulfhydrating protein disulphide isomerase to attenuate atherosclerosis

Hyperhomocysteinaemia (HHcy)‐impaired endothelial dysfunction including endoplasmic reticulum (ER) stress plays a crucial role in atherogenesis. Hydrogen sulphide (H(2)S), a metabolic production of Hcy and gasotransmitter, exhibits preventing cardiovascular damages induced by HHcy by reducing ER str...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Jiang, Shan, Xu, Wenjing, Chen, Zhenzhen, Cui, Changting, Fan, Xiaofang, Cai, Jun, Gong, Yongsheng, Geng, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034471/
https://ncbi.nlm.nih.gov/pubmed/33675119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16423
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