TTN/OBSCN ‘Double‐Hit’ predicts favourable prognosis, ‘immune‐hot’ subtype and potentially better immunotherapeutic efficacy in colorectal cancer

Colorectal cancer (CRC) remains a leading cause of cancer‐related deaths worldwide. Although treatment strategies for solid tumours have been revolutionized by immunotherapy, only a small subset of CRC patients benefit. Using two‐independent cohorts, we found the common frequently mutated genes TTN...

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Pubblicato in:J Cell Mol Med
Autori principali: Liu, Zaoqu, Wang, Libo, Guo, Chunguang, Liu, Long, Jiao, Dechao, Sun, Zhenqiang, Wu, Kunpeng, Zhao, Yanan, Han, Xinwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034451/
https://ncbi.nlm.nih.gov/pubmed/33624434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16393
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