Biosimilar or Not: Physicochemical and Biological Characterization of MabThera and Its Two Biosimilar Candidates

[Image: see text] The development of therapeutic biosimilar antibodies has become an important driving force of the modern biopharmaceutical industry. In this study, physiochemical characteristics (amino acid sequence, intact/subunit molecular weight, isoelectric point, post-translation modification...

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Vydáno v:ACS Pharmacol Transl Sci
Hlavní autoři: Wang, Hong, Wu, Linping, Wang, Can, Xu, Jin, Yin, Hongrui, Guo, Huaizu, Zheng, Luxia, Shao, Hong, Chen, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033751/
https://ncbi.nlm.nih.gov/pubmed/33860202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00225
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